155 Results for "

Nauclea officinalis (Pirre ex Pitard) Merr.

" in MedChemExpress (MCE) Product Catalog:
Products (155)

155 Results for "Nauclea officinalis (Pirre ex Pitard) Merr." in MCE Product Catalog:

10
10 Publications Verification
Cat. No.: HY-10912
CAS No.: 574013-66-4
Purity:  99.24%
Target:  

FXR Autophagy

Research Areas:  

Others

Fexaramine is a potent and selective FXR agonist with an EC50 of 25 nM. Fexaramine has no activity against hRXRα, hPPARαγδ, mPXR, hPXR, hLXRα, hTRβ, hRARβ, mCAR, mERRγ, and hVDR receptors .
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8
8 Cited Publications
Cat. No.: HY-N0163
CAS No.: 528-43-8
Magnolol, a natural lignan isolated from the stem bark of Magnolia officinalis, is a dual agonist of both RXRα and PPARγ, with EC50 values of 10.4 µM and 17.7 µM, respectively.
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7
7 Cited Publications
Cat. No.: HY-N0631
CAS No.: 131189-57-6
Cornuside is an iridoid glycoside with anti-allergic, anti-inflammatory, and neuroprotective activities. Cornuside exerts anti-allergic activity by downregulating the p38 MAPK, JNK, and NF-κB signaling pathways, and inhibits IgE-mediated histamine release from mast cells. Cornuside improves cognitive impairment in mice by inhibiting BACE1 activity (IC50 = 55.84 μg/mL) and enhancing ChAT activity. Cornuside inhibits LPS (HY-D1056)-induced inflammatory mediators, including iNOS, COX-2, PGE2, TNF-α, IL-6, and IL-1β, by suppressing NF-κB activation .
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5
5 Cited Publications
Cat. No.: HY-N1390
CAS No.: 134-96-3
Syringaldehyde is a polyphenolic compound belonging to the group of flavonoids and is found in different plant species like Manihot esculenta and Magnolia officinalis . Syringaldehyde moderately inhibits COX-2 activity with an IC50 of 3.5 μg/mL . Anti-hyperglycemic and anti-inflammatory activities .
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4
4 Cited Publications
Cat. No.: HY-50730
CAS No.: 2224-02-4
Asparagusic acid is a sulfur-containing flavor component produced by Asparagus officinalis Linn., with anti-parasitic effect. Asparagusic acid is a plant growth inhibitor .
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3
3 Cited Publications
Cat. No.: HY-N0648
CAS No.: 5945-50-6
Monotropein is an iridoid glycoside that can be isolated from the roots of Morinda officinalis. Monotropein inhibits the expression of inflammatory mediators in dextran sulfate sodium (DSS)-induced colitis mouse model. Monotropein exerts protective effects against IL-1β-induced apoptosis and catabolic responses on osteoarthritis chondrocytes. Monotropein has cartilage protective activity. Monotropein can alleviate Cisplatin (HY-17394)-induced acute kidney injury by inhibiting oxidative damage, inflammation and apoptosis through activation of Nrf2/HO-1 pathway and inhibition of NF-κB signaling. Monotropein can be studied in research for osteoarthritis, acute kidney injury and acute lung injury .
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2
2 Cited Publications
Cat. No.: HY-N0530
CAS No.: 12777-70-7
Synonyms: Dryocrassin
Dryocrassin ABBA (Dryocrassin) is an orally active phloroglucinol derivative that can be extracted from Phyllopteris officinalis. Dryocrassin ABBA has antitumor and antiviral activity. Dryocrassin ABBA induced apoptosis of human hepatocellular carcinoma cells through mitochondrial pathway mediated by Caspase .
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2
2 Cited Publications
Cat. No.: HY-N0173
CAS No.: 485-71-2
Synonyms: α-Quinidine
Cinchonidine (α-Quinidine) is a cinchona alkaloid found in Cinchona officinalis and Gongronema latifolium. A building block used in asymmetric synthesis in organic chemistry. Weak inhibitor of serotonin transporter (SERT) with Kis of 330, 4.2, 36, 196, 15 μM for dSERT, hSERT, hSERT I172M, hSERT S438T, hSERT Y95F, respectively. Antimalarial activities .
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2
2 Cited Publications
Cat. No.: HY-N2014
CAS No.: 548-37-8
Verbenalin is an orally active terpenoid glycoside that can be extracted from the medicinal plant Verbena officinalis. Verbenalin has anti-inflammatory, antiviral, and neuroprotective effects. Verbenalin has a strong binding affinity to the nsp-12 protein of the SARS-CoV-2 virus. Verbenalin can be used in the research of inflammatory and nervous system diseases such as hepatitis and Alzheimer's disease .
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1
1 Cited Publications
Cat. No.: HY-N7269
CAS No.: 96400-45-2
Luteolin 7-diglucuronide is the major flavonoid isolated from Aloysia triphylla and Verbena officinalis .
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1
1 Cited Publications
Cat. No.: HY-N4099
CAS No.: 53527-42-7
Luteolin-3-O-beta-D-glucuronide, a glucuronide derivative of Luteolin (HY-N0162), is found in the leaves of Rosmarinus officinalis L. Luteolin-3-O-beta-D-glucuronide inhibits nitrite production in macrophages and binds strongly to FYN kinase .
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1
1 Cited Publications
Cat. No.: HY-136150
CAS No.: 82684-06-8
Methyl camosate is a diterpene isolated from Salvia officinalis or Rosmarinus officinalis. Methyl camosate has potent antioxidant and anti-bacterial activity .
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1
1 Cited Publications
Cat. No.: HY-N4290
CAS No.: 25499-90-5
3-Epioleanolic acid is an active component of Verbena officinalis Linn, with anti-inflammatory activity .
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1
1 Cited Publications
Cat. No.: HY-N12492
CAS No.: 25460-12-2
11,12-Di-O-methylcarnosol (Comp 7) is a nolic diterpene lactone that can be isolated from leaves of rosemary (Rosmarinus officinalis L.) .
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1
1 Cited Publications
Cat. No.: HY-Y0051
CAS No.: 67-47-0
Synonyms: 2-Hydroxymethyl-5-furfural; 2-Formyl-5-hydroxymethylfuran
5-Hydroxymethylfurfural (2-Hydroxymethyl-5-furfural), derived from Cornus officinalis, inhibits yeast growth and fermentation as stressors.
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1
1 Cited Publications
Cat. No.: HY-N4191
CAS No.: 93780-80-4
Isorosmanol is an abietane-type diterpene isolated from Rosmarinus officinalis L. aerial parts, with antioxidant, neuroprotective and neurotrophic effects. Isorosmanol inhibits AChE activity and melanin synthesis .
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1
1 Cited Publications
Cat. No.: HY-N0332
CAS No.: 35286-59-0
Ziyuglycoside II is a triterpenoid saponin compound extracted from Sanguisorba officinalis L.. Ziyuglycoside II induces reactive oxygen species (ROS) production and apoptosis. Anti-inflammation and anti-cancer effect .
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1
1 Cited Publications
Cat. No.: HY-133708
CAS No.: 13405-60-2
Purity:  99.82%
Synonyms: Glucogallin; 1-O-Galloyl-β-D-glucose
β-Glucogallin is an orally active and selective aldose reductase (AKR1B1) inhibitor with an IC50 value of 58 μM when using Glyceraldehyde (HY-128748) as AKR1B1 substrate. β-Glucogallin reduces ROS, PDGF, RAGE, and NF-κB. β-Glucogallin increases SOD. β-Glucogallin has antioxidant and hepatoprotective effects. β-Glucogallin can be used in retinal research .
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1
1 Cited Publications
Cat. No.: HY-N0331
CAS No.: 35286-58-9
Ziyuglycoside I isolated from S. officinalis root, has anti-wrinkle activity, and increases the expression of type I collagen. Ziyuglycoside I could be used as an active ingredient for cosmetics . Ziyuglycoside I triggers cell cycle arrest and apoptosis mediated by p53, it can be a potential agent candidate for treating triple-negative breast cancer (TNBC) .
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Cat. No.: HY-N2015
CAS No.: 50816-24-5
Hastatoside is an iridoid glycoside that is isolated from Verbena officinalis and has a role in promoting sleep .
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